Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach

Signet-ring cell carcinoma (SRCC) is a unique subtype of gastric cancer that is impaired for cell–cell adhesion. The pathogenesis of SRCC remains unclear. Here, we show that expression of kinesin-associated protein 3 (KAP3), a cargo adaptor subunit of the kinesin superfamily protein 3 (KIF3), a moto...

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Detalles Bibliográficos
Autores principales: Soda, Tomohiro, Gen, Yasuyuki, Terasaki, Kei, Iwai, Naoto, Kitaichi, Tomoko, Dohi, Osamu, Taketani, Hiroyoshi, Seko, Yuya, Umemura, Atsushi, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito, Yasui, Kohichiroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943207/
https://www.ncbi.nlm.nih.gov/pubmed/35322078
http://dx.doi.org/10.1038/s41598-022-08904-8

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