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Syringic and ascorbic acids prevent NDMA-induced pulmonary fibrogenesis, inflammation, apoptosis, and oxidative stress through the regulation of PI3K-Akt/PKB-mTOR-PTEN signaling pathway

Idiopathic lung fibrosis (ILF) is a severe and life threatening lung disorder that is characterized by scarring of lung tissue, leading to thickening and stiffening of affected areas. This study looked at the role played by PI3K-Akt/PKB-mToR signaling pathway in the pathogenesis of N-Nitrosodimethyl...

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Detalles Bibliográficos
Autores principales: Somade, Oluwatobi T., Adeyi, Olubisi E., Ajayi, Babajide O., Asunde, Osiro O., Iloh, Precious D., Adesanya, Adedayo A., Babalola, Olanrewaju I., Folorunsho, Oluwaseyi T., Olakunle, Deborah A., Lawal, Opeyemi F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943260/
https://www.ncbi.nlm.nih.gov/pubmed/35340717
http://dx.doi.org/10.1016/j.metop.2022.100179