Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer

A 67-year-old man with a history of esophageal cancer resection was referred to our hospital because of nausea and appetite loss. Laboratory findings showed severe hyponatremia and were compatible with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Chest computed tomography (CT) r...

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Autores principales: Koizumi, Tomonobu, Kobayashi, Takashi, Kanda, Shintaro, Fukushima, Toshirou, Muranaka, Futoshi, Miura, Kentaro, Asaka, Shiho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943389/
https://www.ncbi.nlm.nih.gov/pubmed/35228477
http://dx.doi.org/10.2169/internalmedicine.8223-21
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author Koizumi, Tomonobu
Kobayashi, Takashi
Kanda, Shintaro
Fukushima, Toshirou
Muranaka, Futoshi
Miura, Kentaro
Asaka, Shiho
author_facet Koizumi, Tomonobu
Kobayashi, Takashi
Kanda, Shintaro
Fukushima, Toshirou
Muranaka, Futoshi
Miura, Kentaro
Asaka, Shiho
author_sort Koizumi, Tomonobu
collection PubMed
description A 67-year-old man with a history of esophageal cancer resection was referred to our hospital because of nausea and appetite loss. Laboratory findings showed severe hyponatremia and were compatible with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Chest computed tomography (CT) revealed a nodule measuring 13 mm in the lower lobe of the right lung. Right thoracotomy was performed, and the histopathological diagnosis was small-cell lung cancer (T1bN0M0; Stage 1b). Although SIADH is frequently associated with small-cell lung cancer, it is extremely rare as the initial clinical feature in stage I small-cell lung cancer.
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spelling pubmed-89433892022-04-14 Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer Koizumi, Tomonobu Kobayashi, Takashi Kanda, Shintaro Fukushima, Toshirou Muranaka, Futoshi Miura, Kentaro Asaka, Shiho Intern Med Case Report A 67-year-old man with a history of esophageal cancer resection was referred to our hospital because of nausea and appetite loss. Laboratory findings showed severe hyponatremia and were compatible with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Chest computed tomography (CT) revealed a nodule measuring 13 mm in the lower lobe of the right lung. Right thoracotomy was performed, and the histopathological diagnosis was small-cell lung cancer (T1bN0M0; Stage 1b). Although SIADH is frequently associated with small-cell lung cancer, it is extremely rare as the initial clinical feature in stage I small-cell lung cancer. The Japanese Society of Internal Medicine 2022-03-01 2022-03-01 /pmc/articles/PMC8943389/ /pubmed/35228477 http://dx.doi.org/10.2169/internalmedicine.8223-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Koizumi, Tomonobu
Kobayashi, Takashi
Kanda, Shintaro
Fukushima, Toshirou
Muranaka, Futoshi
Miura, Kentaro
Asaka, Shiho
Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title_full Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title_fullStr Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title_full_unstemmed Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title_short Syndrome of Inappropriate Antidiuretic Hormone Secretion as the Initial Presentation in a Patient with Stage I Small-cell Lung Cancer
title_sort syndrome of inappropriate antidiuretic hormone secretion as the initial presentation in a patient with stage i small-cell lung cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943389/
https://www.ncbi.nlm.nih.gov/pubmed/35228477
http://dx.doi.org/10.2169/internalmedicine.8223-21
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