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Exogenous spermine inhibits high glucose/oxidized LDL-induced oxidative stress and macrophage pyroptosis by activating the Nrf2 pathway

Evidence suggests that macrophage pyroptosis promotes the progression of diabetic atherosclerosis. Spermine, a natural cellular metabolite, demonstrates a protective effect against cardiovascular diseases. However, whether spermine has a protective effect against macrophage pyroptosis caused by high...

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Detalles Bibliográficos
Autores principales:	Qiu, Yuxuan, Li, Linna, Guo, Xiaohui, Liu, Jiangwen, Xu, Liang, Li, Yanbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943647/ https://www.ncbi.nlm.nih.gov/pubmed/35350102 http://dx.doi.org/10.3892/etm.2022.11239

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