Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis

Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes,...

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Autores principales: Barbosa, Joycilene da Silva, da Silva, Geraldo Bezerra, Meneses, Gdayllon Cavalcante, Martins, Alice Maria Costa, Daher, Elizabeth De Francesco, Machado, Rosângela Pinheiro Gonçalves, Lemes, Romélia Pinheiro Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943868/
https://www.ncbi.nlm.nih.gov/pubmed/34846061
http://dx.doi.org/10.1590/2175-8239-JBN-2020-0222
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author Barbosa, Joycilene da Silva
da Silva, Geraldo Bezerra
Meneses, Gdayllon Cavalcante
Martins, Alice Maria Costa
Daher, Elizabeth De Francesco
Machado, Rosângela Pinheiro Gonçalves
Lemes, Romélia Pinheiro Gonçalves
author_facet Barbosa, Joycilene da Silva
da Silva, Geraldo Bezerra
Meneses, Gdayllon Cavalcante
Martins, Alice Maria Costa
Daher, Elizabeth De Francesco
Machado, Rosângela Pinheiro Gonçalves
Lemes, Romélia Pinheiro Gonçalves
author_sort Barbosa, Joycilene da Silva
collection PubMed
description Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. AKI may progress to chronic kidney disease (CKD), a condition linked with dialysis and greater risk of cardiovascular disease. This review article aims to discuss cases of AKI in preterm newborns with sepsis, the use of biomarkers in lab workup, and the use of non-conventional biomarkers for the early identification of AKI.
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spelling pubmed-89438682022-04-04 Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis Barbosa, Joycilene da Silva da Silva, Geraldo Bezerra Meneses, Gdayllon Cavalcante Martins, Alice Maria Costa Daher, Elizabeth De Francesco Machado, Rosângela Pinheiro Gonçalves Lemes, Romélia Pinheiro Gonçalves J Bras Nefrol Review Articles Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. AKI may progress to chronic kidney disease (CKD), a condition linked with dialysis and greater risk of cardiovascular disease. This review article aims to discuss cases of AKI in preterm newborns with sepsis, the use of biomarkers in lab workup, and the use of non-conventional biomarkers for the early identification of AKI. Sociedade Brasileira de Nefrologia 2021-11-29 2022 /pmc/articles/PMC8943868/ /pubmed/34846061 http://dx.doi.org/10.1590/2175-8239-JBN-2020-0222 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Barbosa, Joycilene da Silva
da Silva, Geraldo Bezerra
Meneses, Gdayllon Cavalcante
Martins, Alice Maria Costa
Daher, Elizabeth De Francesco
Machado, Rosângela Pinheiro Gonçalves
Lemes, Romélia Pinheiro Gonçalves
Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title_full Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title_fullStr Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title_full_unstemmed Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title_short Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
title_sort use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943868/
https://www.ncbi.nlm.nih.gov/pubmed/34846061
http://dx.doi.org/10.1590/2175-8239-JBN-2020-0222
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