Exosomal CagA from Helicobacter pylori aggravates intestinal epithelium barrier dysfunction in chronic colitis by facilitating Claudin-2 expression

BACKGROUND: The chronic infection with Helicobacter pylori (H. pylori), especially cytotoxin-associated gene A-positive (CagA(+)) strains, has been associated with various extragastric disorders. Evaluating the potential impacts of virulence factor CagA on intestine may provide a better understandin...

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Detalles Bibliográficos
Autores principales: Guo, Yinjie, Xu, Canxia, Gong, Renjie, Hu, Tingzi, Zhang, Xue, Xie, Xiaoran, Chi, Jingshu, Li, Huan, Xia, Xiujuan, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944046/
https://www.ncbi.nlm.nih.gov/pubmed/35331316
http://dx.doi.org/10.1186/s13099-022-00486-0

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