DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome—including in elderly patients

Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. We aimed at identifying age-related molecular differences that would justify and guide distinct treatment decisions in elderly glio...

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Detalles Bibliográficos
Autores principales: Bady, Pierre, Marosi, Christine, Weller, Michael, Grønberg, Bjørn H., Schultz, Henrik, Taphoorn, Martin J. B., Gijtenbeek, Johanna M. M., van den Bent, Martin J., von Deimling, Andreas, Stupp, Roger, Malmström, Annika, Hegi, Monika E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944086/
https://www.ncbi.nlm.nih.gov/pubmed/35331339
http://dx.doi.org/10.1186/s40478-022-01344-5

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