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Trends in platelet count among cancer patients
An elevated platelet count has been associated with an increased incidence of cancer and poor survival for many cancer types. In this study, platelet levels were captured among cancer patients in the 2 years prior to and following a cancer diagnosis. I investigated if the trends in platelet count di...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944120/ https://www.ncbi.nlm.nih.gov/pubmed/35331331 http://dx.doi.org/10.1186/s40164-022-00272-3 |
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author | Giannakeas, Vasily |
author_facet | Giannakeas, Vasily |
author_sort | Giannakeas, Vasily |
collection | PubMed |
description | An elevated platelet count has been associated with an increased incidence of cancer and poor survival for many cancer types. In this study, platelet levels were captured among cancer patients in the 2 years prior to and following a cancer diagnosis. I investigated if the trends in platelet count differ between patients that died or did not die from their cancer. For many cancer types, including colon, lung, ovary, and stomach, platelet counts rose as they approached the date of diagnosis. Patients that died from their cancer within 3 years of diagnosis had a higher peak platelet count than those who survived. Following diagnosis, platelet count was elevated among patients that died from their cancer as compared to patients who survived. An elevated platelet count could potentially indicate the presence of an occult cancer or be used as a prognostic measure for cancer-specific survival. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40164-022-00272-3. |
format | Online Article Text |
id | pubmed-8944120 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-89441202022-03-25 Trends in platelet count among cancer patients Giannakeas, Vasily Exp Hematol Oncol Letter to the Editor An elevated platelet count has been associated with an increased incidence of cancer and poor survival for many cancer types. In this study, platelet levels were captured among cancer patients in the 2 years prior to and following a cancer diagnosis. I investigated if the trends in platelet count differ between patients that died or did not die from their cancer. For many cancer types, including colon, lung, ovary, and stomach, platelet counts rose as they approached the date of diagnosis. Patients that died from their cancer within 3 years of diagnosis had a higher peak platelet count than those who survived. Following diagnosis, platelet count was elevated among patients that died from their cancer as compared to patients who survived. An elevated platelet count could potentially indicate the presence of an occult cancer or be used as a prognostic measure for cancer-specific survival. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40164-022-00272-3. BioMed Central 2022-03-24 /pmc/articles/PMC8944120/ /pubmed/35331331 http://dx.doi.org/10.1186/s40164-022-00272-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Letter to the Editor Giannakeas, Vasily Trends in platelet count among cancer patients |
title | Trends in platelet count among cancer patients |
title_full | Trends in platelet count among cancer patients |
title_fullStr | Trends in platelet count among cancer patients |
title_full_unstemmed | Trends in platelet count among cancer patients |
title_short | Trends in platelet count among cancer patients |
title_sort | trends in platelet count among cancer patients |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944120/ https://www.ncbi.nlm.nih.gov/pubmed/35331331 http://dx.doi.org/10.1186/s40164-022-00272-3 |
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