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Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial
BACKGROUND AND AIMS: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944375/ https://www.ncbi.nlm.nih.gov/pubmed/35340973 http://dx.doi.org/10.4103/joacp.JOACP_54_20 |
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author | Ghaderi, Kamal Rahmani, Khaled Rahmanpanah, Nasser Shami, Shoaleh Zahedi, Farhad Nasseri, Karim |
author_facet | Ghaderi, Kamal Rahmani, Khaled Rahmanpanah, Nasser Shami, Shoaleh Zahedi, Farhad Nasseri, Karim |
author_sort | Ghaderi, Kamal |
collection | PubMed |
description | BACKGROUND AND AIMS: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB in distal forearm and hand surgery. MATERIAL AND METHODS: In this randomized double-blind trial, which was conducted after obtaining institutional ethical committee approval, 60 patients were enrolled and randomly divided into two groups. In both groups, the analgesic base of the block was 20 mL lidocaine 0.5% that was supplemented by 1 μg/kg dexmedetomidine in the LD group or 1 mL of 0.9% saline in the LS group. Patients were evaluated for the onset and duration of sensory block, time of the first request for postoperative analgesic, and analgesic request frequency during the first 24 h after surgery. RESULTS: Sensory block onset in the LD group (7.1 ± 1.4 min) compared to the LS group (8.4 ± 1.4) was faster (P = 0.008). Duration of the sensory block in LD group (49.7 ± 7.2 min) was longer than LS group (33.3 ± 2.6) (P < 0.001). Compared to LS group, time of the first request for postoperative analgesic in LD group was later (P = 0.6), and had lesser analgesic requests during the first 24 h after surgery (P < 0.001). CONCLUSION: Based on our study’s finding, adding dexmedetomidine to lidocaine in the MFBB increases the duration of sensory block. |
format | Online Article Text |
id | pubmed-8944375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-89443752022-03-25 Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial Ghaderi, Kamal Rahmani, Khaled Rahmanpanah, Nasser Shami, Shoaleh Zahedi, Farhad Nasseri, Karim J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Forearm Modified Bier Block (FMBB) reduces local anesthetic systemic toxicity risks compared to the traditional method. This study was designed and implemented to compare the effects of lidocaine–dexmedetomidine (LD) and lidocaine–saline (LS) on the characteristics of the MFBB in distal forearm and hand surgery. MATERIAL AND METHODS: In this randomized double-blind trial, which was conducted after obtaining institutional ethical committee approval, 60 patients were enrolled and randomly divided into two groups. In both groups, the analgesic base of the block was 20 mL lidocaine 0.5% that was supplemented by 1 μg/kg dexmedetomidine in the LD group or 1 mL of 0.9% saline in the LS group. Patients were evaluated for the onset and duration of sensory block, time of the first request for postoperative analgesic, and analgesic request frequency during the first 24 h after surgery. RESULTS: Sensory block onset in the LD group (7.1 ± 1.4 min) compared to the LS group (8.4 ± 1.4) was faster (P = 0.008). Duration of the sensory block in LD group (49.7 ± 7.2 min) was longer than LS group (33.3 ± 2.6) (P < 0.001). Compared to LS group, time of the first request for postoperative analgesic in LD group was later (P = 0.6), and had lesser analgesic requests during the first 24 h after surgery (P < 0.001). CONCLUSION: Based on our study’s finding, adding dexmedetomidine to lidocaine in the MFBB increases the duration of sensory block. Wolters Kluwer - Medknow 2021 2021-12-15 /pmc/articles/PMC8944375/ /pubmed/35340973 http://dx.doi.org/10.4103/joacp.JOACP_54_20 Text en Copyright: © 2021 Journal of Anaesthesiology Clinical Pharmacology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Ghaderi, Kamal Rahmani, Khaled Rahmanpanah, Nasser Shami, Shoaleh Zahedi, Farhad Nasseri, Karim Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title_full | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title_fullStr | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title_full_unstemmed | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title_short | Comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: A clinical trial |
title_sort | comparison of lidocaine–dexmedetomidine and lidocaine–saline on the characteristics of the modified forearm bier block: a clinical trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944375/ https://www.ncbi.nlm.nih.gov/pubmed/35340973 http://dx.doi.org/10.4103/joacp.JOACP_54_20 |
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