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Intravitreal Injection of PACAP Attenuates Acute Ocular Hypertension–Induced Retinal Injury Via Anti-Apoptosis and Anti-Inflammation in Mice

PURPOSE: Pituitary adenylate cyclase-activating polypeptide (PACAP) has shown potent neuroprotective effects in central nervous system and retina disorders. However, whether PACAP can attenuate retinal neurodegeneration induced by acute ocular hypertension (AOH) and the underlying mechanisms remain...

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Detalles Bibliográficos
Autores principales: Lu, Peng, Shi, Yuxun, Ye, Dan, Lu, Xi, Tang, Xiaoyu, Cheng, Lu, Xu, Yue, Huang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944396/
https://www.ncbi.nlm.nih.gov/pubmed/35293951
http://dx.doi.org/10.1167/iovs.63.3.18