RecA and Specialized Error-Prone DNA Polymerases Are Not Required for Mutagenesis and Antibiotic Resistance Induced by Fluoroquinolones in Pseudomonas aeruginosa

To cope with stressful conditions, including antibiotic exposure, bacteria activate the SOS response, a pathway that induces error-prone DNA repair and mutagenesis mechanisms. In most bacteria, the SOS response relies on the transcriptional repressor LexA and the co-protease RecA, the latter being a...

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Detalles Bibliográficos
Autores principales: Mercolino, Jessica, Lo Sciuto, Alessandra, Spinnato, Maria Concetta, Rampioni, Giordano, Imperi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944484/
https://www.ncbi.nlm.nih.gov/pubmed/35326787
http://dx.doi.org/10.3390/antibiotics11030325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944484/
https://www.ncbi.nlm.nih.gov/pubmed/35326787
http://dx.doi.org/10.3390/antibiotics11030325

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