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The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity

Mitochondrial division inhibitor-1 (mdivi-1), a non-specific inhibitor of Drp1-dependent mitochondrial fission, is neuroprotective in numerous preclinical disease models. These include rodent models of Alzheimer’s disease and ischemic or traumatic brain injury. Among its Drp1-independent actions, th...

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Detalles Bibliográficos
Autores principales: Bordt, Evan A., Zhang, Naibo, Waddell, Jaylyn, Polster, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944504/
https://www.ncbi.nlm.nih.gov/pubmed/35326100
http://dx.doi.org/10.3390/antiox11030450