Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation

Heme oxygenase-1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also regarded as a protective protein with an immunoregulation role in asthmatic airway inflammation. HO-1 exerts an anti-inflammation role in different stages of airway inflammation via regulating various immune ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Zhenwei, Zhong, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944570/
https://www.ncbi.nlm.nih.gov/pubmed/35326116
http://dx.doi.org/10.3390/antiox11030465
_version_ 1784673748256817152
author Xia, Zhenwei
Zhong, Wenwei
author_facet Xia, Zhenwei
Zhong, Wenwei
author_sort Xia, Zhenwei
collection PubMed
description Heme oxygenase-1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also regarded as a protective protein with an immunoregulation role in asthmatic airway inflammation. HO-1 exerts an anti-inflammation role in different stages of airway inflammation via regulating various immune cells, such as dendritic cells, mast cells, basophils, T cells, and macrophages. In addition, the immunoregulation role of HO-1 may differ according to subcellular locations.
format Online
Article
Text
id pubmed-8944570
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-89445702022-03-25 Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation Xia, Zhenwei Zhong, Wenwei Antioxidants (Basel) Review Heme oxygenase-1 (HO-1) is not only a rate-limiting enzyme in heme metabolism but is also regarded as a protective protein with an immunoregulation role in asthmatic airway inflammation. HO-1 exerts an anti-inflammation role in different stages of airway inflammation via regulating various immune cells, such as dendritic cells, mast cells, basophils, T cells, and macrophages. In addition, the immunoregulation role of HO-1 may differ according to subcellular locations. MDPI 2022-02-26 /pmc/articles/PMC8944570/ /pubmed/35326116 http://dx.doi.org/10.3390/antiox11030465 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xia, Zhenwei
Zhong, Wenwei
Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title_full Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title_fullStr Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title_full_unstemmed Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title_short Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
title_sort immune regulation of heme oxygenase-1 in allergic airway inflammation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944570/
https://www.ncbi.nlm.nih.gov/pubmed/35326116
http://dx.doi.org/10.3390/antiox11030465
work_keys_str_mv AT xiazhenwei immuneregulationofhemeoxygenase1inallergicairwayinflammation
AT zhongwenwei immuneregulationofhemeoxygenase1inallergicairwayinflammation

Ejemplares similares