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Lung-Targeted Delivery of Dimethyl Fumarate Promotes the Reversal of Age-Dependent Established Lung Fibrosis

Idiopathic pulmonary fibrosis (IPF), a severe and deadly form of lung fibrosis, is widely regarded as a disease of aging. We previously demonstrated that aged mice with persistent lung fibrosis and IPF lung myofibroblasts exhibit deficient Nrf2-mediated antioxidant responses. Tecfidera is an orally...

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Detalles Bibliográficos
Autores principales:	Kato, Kosuke, Papageorgiou, Ioannis, Shin, Yoon-Joo, Kleinhenz, Jennifer M., Palumbo, Sunny, Hahn, Seongmin, Irish, Joseph D., Rounseville, Skye P., Knox, Kenneth S., Hecker, Louise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944574/ https://www.ncbi.nlm.nih.gov/pubmed/35326142 http://dx.doi.org/10.3390/antiox11030492

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