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Correlation between structure and function in phosphatidylinositol lipid–dependent Kir2.2 gating
Inward rectifier K(+)(Kir) channels regulate cell membrane potential. Different Kir channels respond to unique ligands, but all are regulated by phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). Using planar lipid bilayers, we show that Kir2.2 exhibits bursts of openings separated by long quiesce...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944589/ https://www.ncbi.nlm.nih.gov/pubmed/35286194 http://dx.doi.org/10.1073/pnas.2114046119 |