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Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells

Inhaled polymyxins are increasingly used to treat pulmonary infections caused by multidrug-resistant Gram-negative pathogens. We have previously shown that apoptotic pathways, autophagy and oxidative stress are involved in polymyxin-induced toxicity in human lung epithelial cells. In the present stu...

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Detalles Bibliográficos
Autores principales:	Li, Mengyao, Azad, Mohammad A. K., Ahmed, Maizbha U., Zhu, Yan, Song, Jiangning, Zhou, Fanfan, Chan, Hak-Kim, Velkov, Tony, Zhou, Qi Tony, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944768/ https://www.ncbi.nlm.nih.gov/pubmed/35326770 http://dx.doi.org/10.3390/antibiotics11030307

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