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Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix
[Image: see text] Tandem-repeat proteins comprise small secondary structure motifs that stack to form one-dimensional arrays with distinctive mechanical properties that are proposed to direct their cellular functions. Here, we use single-molecule optical tweezers to study the folding of consensus-de...
Autores principales: | Synakewicz, Marie, Eapen, Rohan S., Perez-Riba, Albert, Rowling, Pamela J. E., Bauer, Daniela, Weißl, Andreas, Fischer, Gerhard, Hyvönen, Marko, Rief, Matthias, Itzhaki, Laura S., Stigler, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944806/ https://www.ncbi.nlm.nih.gov/pubmed/35258937 http://dx.doi.org/10.1021/acsnano.1c09162 |
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