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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy
Squamous cell carcinoma of the head and neck (SCCHN) is a devastating disease that continues to have low cure rates despite the recent advances in therapies. Cisplatin is the most used chemotherapy agent, and treatment failure is largely driven by resistance to this drug. Amplification of chromosoma...
Autores principales: | Vyas, Avani, Gomez-Casal, Roberto, Cruz-Rangel, Silvia, Villanueva, Hugo, Sikora, Andrew G., Rajagopalan, Pavithra, Basu, Devraj, Pacheco, Jonathan, Hammond, Gerald R. V., Kiselyov, Kirill, Duvvuri, Umamaheswar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944912/ https://www.ncbi.nlm.nih.gov/pubmed/35286200 http://dx.doi.org/10.1073/pnas.2100670119 |
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