Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages

Activated macrophages must carefully calibrate their inflammatory responses to balance efficient pathogen control with inflammation-mediated tissue damage, but the molecular underpinnings of this “balancing act” remain unclear. Using genetically engineered mouse models and primary macrophage culture...

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Detalles Bibliográficos
Autores principales: Alam, Zahidul, Devalaraja, Samir, Li, Minghong, To, Tsun Ki Jerrick, Folkert, Ian W., Mitchell-Velasquez, Erick, Dang, Mai T., Young, Patricia, Wilbur, Christopher J., Silverman, Michael A., Li, Xinyuan, Chen, Youhai H., Hernandez, Paul T., Bhattacharyya, Aritra, Bhattacharya, Mallar, Levine, Matthew H., Haldar, Malay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944937/
https://www.ncbi.nlm.nih.gov/pubmed/32610126
http://dx.doi.org/10.1016/j.celrep.2020.107825

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