Extracellular Vesicles Derived from Mesenchymal Stromal Cells Delivered during Hypothermic Oxygenated Machine Perfusion Repair Ischemic/Reperfusion Damage of Kidneys from Extended Criteria Donors

SIMPLE SUMMARY: In this study, we explore for the first time an innovative tool for organ preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from expanded criteria donors (ECD) unsuitable for transplantation. Ex vivo hypothermic oxygenated perfusion (HOPE) with an...

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Detalles Bibliográficos
Autores principales: Rampino, Teresa, Gregorini, Marilena, Germinario, Giuliana, Pattonieri, Eleonora Francesca, Erasmi, Fulvia, Grignano, Maria Antonietta, Bruno, Stefano, Alomari, Esra, Bettati, Stefano, Asti, Annalia, Ramus, Marina, De Amici, Mara, Testa, Giorgia, Bruno, Stefania, Ceccarelli, Gabriele, Serpieri, Nicoletta, Libetta, Carmelo, Sepe, Vincenzo, Blasevich, Flavia, Odaldi, Federica, Maroni, Lorenzo, Vasuri, Francesco, La Manna, Gaetano, Ravaioli, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945029/
https://www.ncbi.nlm.nih.gov/pubmed/35336724
http://dx.doi.org/10.3390/biology11030350

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