Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients

In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics a...

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Detalles Bibliográficos
Autores principales: Revin, Victor, Balykova, Larisa, Pinyaev, Sergey, Syusin, Ilya, Radaeva, Olga, Revina, Nadezhda, Kostina, Yuliya, Kozlov, Evgeniy, Inchina, Vera, Nikitin, Igor, Salikov, Alexandr, Fedorov, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945033/
https://www.ncbi.nlm.nih.gov/pubmed/35327355
http://dx.doi.org/10.3390/biomedicines10030553
Descripción
Sumario:In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods—Raman spectroscopy and laser interference microscopy—is a highly effective method for the diagnosis of SARS-CoV-2.

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