Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients

In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics a...

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Autores principales: Revin, Victor, Balykova, Larisa, Pinyaev, Sergey, Syusin, Ilya, Radaeva, Olga, Revina, Nadezhda, Kostina, Yuliya, Kozlov, Evgeniy, Inchina, Vera, Nikitin, Igor, Salikov, Alexandr, Fedorov, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945033/
https://www.ncbi.nlm.nih.gov/pubmed/35327355
http://dx.doi.org/10.3390/biomedicines10030553
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author Revin, Victor
Balykova, Larisa
Pinyaev, Sergey
Syusin, Ilya
Radaeva, Olga
Revina, Nadezhda
Kostina, Yuliya
Kozlov, Evgeniy
Inchina, Vera
Nikitin, Igor
Salikov, Alexandr
Fedorov, Ilya
author_facet Revin, Victor
Balykova, Larisa
Pinyaev, Sergey
Syusin, Ilya
Radaeva, Olga
Revina, Nadezhda
Kostina, Yuliya
Kozlov, Evgeniy
Inchina, Vera
Nikitin, Igor
Salikov, Alexandr
Fedorov, Ilya
author_sort Revin, Victor
collection PubMed
description In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods—Raman spectroscopy and laser interference microscopy—is a highly effective method for the diagnosis of SARS-CoV-2.
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spelling pubmed-89450332022-03-25 Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients Revin, Victor Balykova, Larisa Pinyaev, Sergey Syusin, Ilya Radaeva, Olga Revina, Nadezhda Kostina, Yuliya Kozlov, Evgeniy Inchina, Vera Nikitin, Igor Salikov, Alexandr Fedorov, Ilya Biomedicines Article In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods—Raman spectroscopy and laser interference microscopy—is a highly effective method for the diagnosis of SARS-CoV-2. MDPI 2022-02-25 /pmc/articles/PMC8945033/ /pubmed/35327355 http://dx.doi.org/10.3390/biomedicines10030553 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Revin, Victor
Balykova, Larisa
Pinyaev, Sergey
Syusin, Ilya
Radaeva, Olga
Revina, Nadezhda
Kostina, Yuliya
Kozlov, Evgeniy
Inchina, Vera
Nikitin, Igor
Salikov, Alexandr
Fedorov, Ilya
Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title_full Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title_fullStr Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title_full_unstemmed Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title_short Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
title_sort research into morphofunctional characteristics of erythrocytes in covid-19 patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945033/
https://www.ncbi.nlm.nih.gov/pubmed/35327355
http://dx.doi.org/10.3390/biomedicines10030553
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