Cargando…

Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma

[Image: see text] The present work describes the development and characterization of liquid crystalline nanoparticles of hispolon (HP-LCNPs) for treating hepatocellular carcinoma. HP-LCNPs were prepared by a top-down method utilizing GMO as the lipid and Pluronic F-127 as the polymeric stabilizer. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ansari, Mohammad Javed, Rahman, Mahfoozur, Alharbi, Khalid S., Altowayan, Waleed M., Ali, Ahmed Mahmoud Abdelhaleem, Almalki, Waleed H., Barkat, Md. Abul, Singh, Tanuja, Nasar, Shehla, Akhter, Md Habban, Beg, Sarwar, Choudhry, Hani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945187/ https://www.ncbi.nlm.nih.gov/pubmed/35350323 http://dx.doi.org/10.1021/acsomega.1c06796

Ejemplares similares

Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment
por: Beg, Sarwar, et al.
Publicado: (2022)

Preparation, Characterization, and Evaluation of Curcumin–Graphene Oxide Complex-Loaded Liposomes against Staphylococcus aureus in Topical Disease
por: Rahman, Mahfoozur, et al.
Publicado: (2022)

Cationic Solid Lipid Nanoparticles of Resveratrol for Hepatocellular Carcinoma Treatment: Systematic Optimization, in vitro Characterization and Preclinical Investigation
por: Rahman, Mahfoozur, et al.
Publicado: (2020)

Emergence of Nano-Based Formulations for Effective Delivery of Flavonoids against Topical Infectious Disorders
por: Dwivedi, Khusbu, et al.
Publicado: (2023)

Bedaquiline-Loaded Solid Lipid Nanoparticles Drug Delivery in the Management of Non-Small-Cell Lung Cancer (NSCLC)
por: Najib Ullah, Shehla Nasar Mir, et al.
Publicado: (2023)

Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives
por: Beg, Sarwar, et al.
Publicado: (2011)

Analgesic Effects and the Mechanisms of Anti-Inflammation of Hispolon in Mice
por: Chang, Heng-Yuan, et al.
Publicado: (2011)

Crotamiton-loaded tea tree oil containing phospholipid-based microemulsion hydrogel for scabies treatment: in vitro, in vivo evaluation, and dermatokinetic studies
por: Chen, Lihua, et al.
Publicado: (2021)

Nanomedicine in the Management of Alzheimer’s Disease: State-of-the-Art
por: Mir Najib Ullah, Shehla Nasar, et al.
Publicado: (2023)

Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System
por: Akhter, Md Habban, et al.
Publicado: (2022)

Hispolon Methyl Ether, a Hispolon Analog, Suppresses the SRC/STAT3/Survivin Signaling Axis to Induce Cytotoxicity in Human Urinary Bladder Transitional Carcinoma Cell Lines
por: Kuo, Min-Yung, et al.
Publicado: (2022)

Empagliflozin induced euglycemic diabetic ketoacidosis. A case reports
por: Altowayan, Waleed M.
Publicado: (2022)

Design-of-Experiment-Assisted Fabrication of Biodegradable Polymeric Nanoparticles: In Vitro Characterization, Biological Activity, and In Vivo Assessment
por: Mir, Mushtaq Ahmad, et al.
Publicado: (2023)

Emergence in the functionalized carbon nanotubes as smart nanocarriers for drug delivery applications
por: Beg, Sarwar, et al.
Publicado: (2018)

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells
por: Hsin, Min-Chieh, et al.
Publicado: (2017)

Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines
por: Poudel, Ishwor, et al.
Publicado: (2022)

Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma
por: Wang, Bin, et al.
Publicado: (2021)

A cross-sectional survey: The “Saudi guidelines for the prevention and management of obesity”: Awareness and adaptation in Al-Qassim province
por: Altowayan, Waleed M., et al.
Publicado: (2022)

Influence of pharmaceutical representatives on prescription decisions by physicians in Qassim province
por: Altowayan, Waleed M., et al.
Publicado: (2022)

Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways
por: Sarfraz, Ayesha, et al.
Publicado: (2020)

Harnessing Folate-Functionalized Nasal Delivery of Dox–Erlo-Loaded Biopolymeric Nanoparticles in Cancer Treatment: Development, Optimization, Characterization, and Biodistribution Analysis
por: Farheen, Ms, et al.
Publicado: (2023)

Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma
por: Rahman, Mahfoozur, et al.
Publicado: (2019)

A cross-sectional survey: knowledge, attitudes, and practices of self-medication in medical and pharmacy students
por: Alduraibi, Razan Khalid, et al.
Publicado: (2022)

The influence of vancomycin on renal functions, the predictors and associated factors for nephrotoxicity
por: Altowayan, Waleed M., et al.
Publicado: (2023)

Toxicity and Antigenotoxic Effect of Hispolon Derivatives: Role of Structure in Modulating Cellular Redox State and Thioredoxin Reductase
por: Chethna, Pogakula, et al.
Publicado: (2018)

A β–Sitosterol Encapsulated Biocompatible Alginate/Chitosan Polymer Nanocomposite for the Treatment of Breast Cancer
por: Afzal, Obaid, et al.
Publicado: (2022)

Impact of Protein Corona on the Biological Identity of Nanomedicine: Understanding the Fate of Nanomaterials in the Biological Milieu
por: Akhter, Md Habban, et al.
Publicado: (2021)

Hispolon Induces Apoptosis, Suppresses Migration and Invasion of Glioblastoma Cells and Inhibits GBM Xenograft Tumor Growth In Vivo
por: Liao, Kuan-Fu, et al.
Publicado: (2021)

Hispolon induces apoptosis in oral squamous cell carcinoma cells through JNK/HO‐1 pathway activation
por: Yang, Wei‐En, et al.
Publicado: (2023)

Surface-Modified Biobased Polymeric Nanoparticles for Dual Delivery of Doxorubicin and Gefitinib in Glioma Cell Lines
por: Farheen, Ms, et al.
Publicado: (2023)

Baicalin-Loaded Lipid–Polymer Hybrid Nanoparticles Inhibiting the Proliferation of Human Colon Cancer: Pharmacokinetics and In Vivo Evaluation
por: Riadi, Yassine, et al.
Publicado: (2023)

Plumbagin-Loaded Glycerosome Gel as Topical Delivery System for Skin Cancer Therapy
por: Md, Shadab, et al.
Publicado: (2021)

Nanotechnology-based inhalation treatments for lung cancer: state of the art
por: Ahmad, Javed, et al.
Publicado: (2015)

Development and Evaluation of Repurposed Etoricoxib Loaded Nanoemulsion for Improving Anticancer Activities against Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2021)

Immunomodulatory Effect of Hispolon on LPS-Induced RAW264.7 Cells and Mitogen/Alloantigen-Stimulated Spleen Lymphocytes of Mice
por: Lee, Eun Kyeong, et al.
Publicado: (2022)

Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity
por: Elmowafy, Mohammed, et al.
Publicado: (2020)

Resveratrol-Loaded Chia Seed Oil-Based Nanogel as an Anti-Inflammatory in Adjuvant-Induced Arthritis
por: Afzal, Obaid, et al.
Publicado: (2023)

Estrogen and Serotonin: Complexity of Interactions and Implications for Epileptic Seizures and Epileptogenesis
por: Pottoo, Faheem Hyder, et al.
Publicado: (2019)

Moringa oleifera leaf extract induces osteogenic-like differentiation of human osteosarcoma SaOS2 cells
por: Khan, Mohammad Idreesh, et al.
Publicado: (2022)

Development of Natural Polysaccharide–Based Nanoparticles of Berberine to Enhance Oral Bioavailability: Formulation, Optimization, Ex Vivo, and In Vivo Assessment
por: Kohli, Kanchan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i5lkdp8kc10tfldnj8nfsruk76