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Prognostic impact of DNMT3A mutation in acute myeloid leukemia with mutated NPM1

The negative prognostic impact of internal tandem duplication of FLT3 (FLT3-ITD) in patients with acute myeloid leukemia with mutated NPM1 (AML-NPM1) is restricted to those with a higher FLT3-ITD allelic ratio (FLT3(high); ≥0.5) and considered negligible in those with a wild-type (FLT3(WT))/low ITD...

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Detalles Bibliográficos
Autores principales:	Oñate, Guadalupe, Bataller, Alex, Garrido, Ana, Hoyos, Montserrat, Arnan, Montserrat, Vives, Susana, Coll, Rosa, Tormo, Mar, Sampol, Antònia, Escoda, Lourdes, Salamero, Olga, Garcia, Antoni, Bargay, Joan, Aljarilla, Alba, Nomdedeu, Josep F., Esteve, Jordi, Sierra, Jorge, Pratcorona, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Myeloid Neoplasia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945292/ https://www.ncbi.nlm.nih.gov/pubmed/34516636 http://dx.doi.org/10.1182/bloodadvances.2020004136

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