ASXL1 and STAG2 are common mutations in GATA2 deficiency patients with bone marrow disease and myelodysplastic syndrome

Patients with GATA2 deficiencyharbor de novo or inherited germline mutations in the GATA2 transcription factor gene, predisposing them to myeloid malignancies. There is considerable variation in disease progression, even among family members with the same mutation in GATA2. We investigated somatic m...

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Detalles Bibliográficos
Autores principales: West, Robert R., Calvo, Katherine R., Embree, Lisa J., Wang, Weixin, Tuschong, Laura M., Bauer, Thomas R., Tillo, Desiree, Lack, Justin, Droll, Stephenie, Hsu, Amy P., Holland, Steven M., Hickstein, Dennis D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945308/
https://www.ncbi.nlm.nih.gov/pubmed/34529785
http://dx.doi.org/10.1182/bloodadvances.2021005065

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