Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Beyond Lipids: The Role in Oxidative Stress and Thrombosis

Proprotein convertase subtilisin/kexin type 9 (PCSK9), mainly secreted in the liver, is a key regulator of cholesterol homeostasis inducing LDL receptors’ degradation. Beyond lipid metabolism, PCSK9 is involved in the development of atherosclerosis, promoting plaque formation in mice and human, impa...

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Detalles Bibliográficos
Autores principales: Cammisotto, Vittoria, Baratta, Francesco, Simeone, Paola G., Barale, Cristina, Lupia, Enrico, Galardo, Gioacchino, Santilli, Francesca, Russo, Isabella, Pignatelli, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945358/
https://www.ncbi.nlm.nih.gov/pubmed/35326219
http://dx.doi.org/10.3390/antiox11030569

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