Cargando…
Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes
Metastatic melanoma is a highly malignant tumor. Melanoma cells release extracellular vesicles (EVs), which contribute to the growth, metastasis, and malignancy of neighboring cells by transfer of tumor-promoting miRNAs, mRNA, and proteins. Melanoma microenvironment acidification promotes tumor prog...
Autores principales: | Bychkov, Maxim L., Kirichenko, Artem V., Mikhaylova, Irina N., Paramonov, Alexander S., Yastremsky, Evgeny V., Kirpichnikov, Mikhail P., Shulepko, Mikhail A., Lyukmanova, Ekaterina N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945455/ https://www.ncbi.nlm.nih.gov/pubmed/35327461 http://dx.doi.org/10.3390/biomedicines10030660 |
Ejemplares similares
-
Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis
por: Bychkov, Maxim L., et al.
Publicado: (2021) -
Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes
por: Bychkov, M. L., et al.
Publicado: (2022) -
Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors
por: Bychkov, Maxim, et al.
Publicado: (2019) -
New Three-Finger Protein from Starfish Asteria rubens Shares Structure and Pharmacology with Human Brain Neuromodulator Lynx2
por: Paramonov, Alexander S., et al.
Publicado: (2022) -
SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer
por: Bychkov, Maxim L., et al.
Publicado: (2021)