Cargando…
Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice
Passive immunotherapy is a very promising approach for the treatment of Alzheimer’s disease (AD). Among the different antibodies under development, those targeting post-translationally modified Aβ peptides might combine efficient reduction in beta-amyloid accompanied by lower sequestration in periph...
Autores principales: | Gnoth, Kathrin, Geissler, Stefanie, Feldhaus, Julia, Taudte, Nadine, Ilse, Victoria, Zürner, Sebastian, Greiser, Sebastian, Braumann, Ulf-Dietrich, Rahfeld, Jens-Ulrich, Cynis, Holger, Schilling, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945487/ https://www.ncbi.nlm.nih.gov/pubmed/35327591 http://dx.doi.org/10.3390/biom12030399 |
Ejemplares similares
-
Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology
por: Gnoth, Kathrin, et al.
Publicado: (2020) -
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice
por: Barendrecht, Susan, et al.
Publicado: (2023) -
Early Detection of Aβ Deposition in the 5xFAD Mouse by Amyloid PET
por: Oh, Se Jong, et al.
Publicado: (2018) -
Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice
por: Prange-Kiel, Janine, et al.
Publicado: (2016) -
Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease
por: Wang, Lu, et al.
Publicado: (2016)