Infigratinib (BGJ 398), a Pan-FGFR Inhibitor, Targets P-Glycoprotein and Increases Chemotherapeutic-Induced Mortality of Multidrug-Resistant Tumor Cells

The microtubule-targeting agents (MTAs) are well-known chemotherapeutic agents commonly used for therapy of a broad spectrum of human malignancies, exhibiting epithelial origin, including breast, lung, and prostate cancer. Despite the impressive response rates shortly after initiation of MTA-based t...

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Detalles Bibliográficos
Autores principales: Boichuk, Sergei, Dunaev, Pavel, Mustafin, Ilshat, Mani, Shinjit, Syuzov, Kirill, Valeeva, Elena, Bikinieva, Firuza, Galembikova, Aigul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945560/
https://www.ncbi.nlm.nih.gov/pubmed/35327403
http://dx.doi.org/10.3390/biomedicines10030601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945560/
https://www.ncbi.nlm.nih.gov/pubmed/35327403
http://dx.doi.org/10.3390/biomedicines10030601

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