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Immunotherapy for SMARCB1-Deficient Sarcomas: Current Evidence and Future Developments

Mutations in subunits of the SWItch Sucrose Non-Fermentable (SWI/SNF) complex occur in 20% of all human tumors. Among these, the core subunit SMARCB1 is the most frequently mutated, and SMARCB1 loss represents a founder driver event in several malignancies, such as malignant rhabdoid tumors (MRT), e...

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Detalles Bibliográficos
Autores principales: Ngo, Carine, Postel-Vinay, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945563/
https://www.ncbi.nlm.nih.gov/pubmed/35327458
http://dx.doi.org/10.3390/biomedicines10030650