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Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance
Despite the eradication of smallpox four decades ago, poxviruses continue to be a threat to humans and animals. The arsenal of anti-poxvirus agents is very limited and understanding mechanisms of resistance to agents targeting viral DNA polymerases is fundamental for the development of antiviral the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945813/ https://www.ncbi.nlm.nih.gov/pubmed/35327382 http://dx.doi.org/10.3390/biomedicines10030580 |