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Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance

Despite the eradication of smallpox four decades ago, poxviruses continue to be a threat to humans and animals. The arsenal of anti-poxvirus agents is very limited and understanding mechanisms of resistance to agents targeting viral DNA polymerases is fundamental for the development of antiviral the...

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Detalles Bibliográficos
Autores principales: Andrei, Graciela, Fiten, Pierre, Krečmerová, Marcela, Opdenakker, Ghislain, Topalis, Dimitrios, Snoeck, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945813/
https://www.ncbi.nlm.nih.gov/pubmed/35327382
http://dx.doi.org/10.3390/biomedicines10030580