Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets

SIMPLE SUMMARY: Thymomas and thymic carcinomas (TCs) are malignant thymic epithelial tumors (TETs) with poor outcome, if non-resectable. Metabolic signatures of TETs have not yet been studied and may offer new therapeutic options. This is the first metabolomics investigation on thymic epithelial tum...

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Detalles Bibliográficos
Autores principales: Alwahsh, Mohammad, Knitsch, Robert, Marchan, Rosemarie, Lambert, Jörg, Hoerner, Christian, Zhang, Xiaonan, Schalke, Berthold, Lee, De-Hyung, Bulut, Elena, Graeter, Thomas, Ott, German, Kurz, Katrin S., Preissler, Gerhard, Schölch, Sebastian, Farhat, Joviana, Yao, Zhihan, Sticht, Carsten, Ströbel, Philipp, Hergenröder, Roland, Marx, Alexander, Belharazem, Djeda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945961/
https://www.ncbi.nlm.nih.gov/pubmed/35326714
http://dx.doi.org/10.3390/cancers14061564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945961/
https://www.ncbi.nlm.nih.gov/pubmed/35326714
http://dx.doi.org/10.3390/cancers14061564

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