Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro

The intake of food with high levels of saturated fatty acids (SatFAs) is associated with the development of obesity and insulin resistance. SatFAs, such as palmitic (PA) and stearic (SA) acids, have been shown to accumulate in the hypothalamus, causing several pathological consequences. Autophagy is...

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Detalles Bibliográficos
Autores principales: Espinosa, Rodrigo, Gutiérrez, Karla, Rios, Javiera, Ormeño, Fernando, Yantén, Liliana, Galaz-Davison, Pablo, Ramírez-Sarmiento, César A., Parra, Valentina, Albornoz, Amelina, Alfaro, Iván E., Burgos, Patricia V., Morselli, Eugenia, Criollo, Alfredo, Budini, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945987/
https://www.ncbi.nlm.nih.gov/pubmed/35326371
http://dx.doi.org/10.3390/cells11060920

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