Cargando…

602 Foot burns in diabetic patients: A single center experience

INTRODUCTION: The most significant sequelae of foot burns in diabetic patients is a non-healing wound that results in a diabetic foot ulcer, which has been a predictor for need for amputation and mortality. Even minor amputations in patients with diabetes have a significant mortality rate. Our syste...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Katherine J, Gillenwater, Justin, Pham, Christopher H, Sheckter, Clifford C, Collier, Zachary J, Dang, Justin, Huang, Samantha, Yenikomshian, Haig A, Garner, Warren L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946110/
http://dx.doi.org/10.1093/jbcr/irac012.230
_version_ 1784674116304896000
author Choi, Katherine J
Gillenwater, Justin
Pham, Christopher H
Sheckter, Clifford C
Collier, Zachary J
Dang, Justin
Huang, Samantha
Yenikomshian, Haig A
Garner, Warren L
author_facet Choi, Katherine J
Gillenwater, Justin
Pham, Christopher H
Sheckter, Clifford C
Collier, Zachary J
Dang, Justin
Huang, Samantha
Yenikomshian, Haig A
Garner, Warren L
author_sort Choi, Katherine J
collection PubMed
description INTRODUCTION: The most significant sequelae of foot burns in diabetic patients is a non-healing wound that results in a diabetic foot ulcer, which has been a predictor for need for amputation and mortality. Even minor amputations in patients with diabetes have a significant mortality rate. Our systemic review found that when 60% of a diabetic patient cohort with foot burns was managed by skin grafting, 29% subsequently required amputations, which is concerning. The practice at our regional burn center has been to manage patients with foot burns and diabetes non-operatively with daily dressing changes, and we believe that this may result in better functional outcomes, ambulatory status, and lower amputation rates. METHODS: A retrospective review of patients with diabetes and foot burns admitted to an ABA verified regional burn center was conducted. The primary outcome was amputation. Secondary outcomes were ambulatory status, wound closure, and infection. Rank sum and fisher exact tests were performed to compare patient demographics, comorbidities, uncontrolled DM (A1c >9%), and burn characteristics between patients who were treated surgically and those who received daily wound care only. These associations were subsequently evaluated with odds ratios (OR) and 95% confidence intervals (CI). A multivariable logistic regression was performed to evaluate for possible differentiating factors that resulted in maintaining ambulatory status at completion of burn care. Statistical significance was defined as p< .05. RESULTS: Of 75 patients identified, median TBSA burned was 2% (IQR 2), and 61% (n=46) had full thickness burns. Mean A1c at admission was 9% (SD 2). In terms of management, 9% (n=7) were treated with debridement and/or skin grafting, and 9% (n=7) later required lower extremity amputations. Infection during first admission developed in 8% (n=6). At completion of burn care, 73% had normal or same ambulatory status, and older patients were less likely to maintain ambulatory status (p=.009, OR=0.92, 95% CI=0.86-0.98). Median time to wound closure was 95 (IQR 130) days, and 12% (n=9) of wounds never fully closed. Burn depth (second vs third degree), burn location (plantar burn vs other areas), uncontrolled DM, and surgical treatment did not result in a statistically significant difference in maintaining ambulatory status at completion of burn care. CONCLUSIONS: Diabetic patients with foot burns are best managed non-operatively with daily dressing changes, and should be allowed to heal secondarily. This may result in a longer time to close the wounds, but the amputation rates were much lower when compared to surgical management. However, 5% of our cohort developed diabetic foot ulcers at completion of burn care, which is a complex disease process that carries a dire prognosis.
format Online
Article
Text
id pubmed-8946110
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-89461102022-03-28 602 Foot burns in diabetic patients: A single center experience Choi, Katherine J Gillenwater, Justin Pham, Christopher H Sheckter, Clifford C Collier, Zachary J Dang, Justin Huang, Samantha Yenikomshian, Haig A Garner, Warren L J Burn Care Res Surgical Care, Acute Non-reconstructive 1 INTRODUCTION: The most significant sequelae of foot burns in diabetic patients is a non-healing wound that results in a diabetic foot ulcer, which has been a predictor for need for amputation and mortality. Even minor amputations in patients with diabetes have a significant mortality rate. Our systemic review found that when 60% of a diabetic patient cohort with foot burns was managed by skin grafting, 29% subsequently required amputations, which is concerning. The practice at our regional burn center has been to manage patients with foot burns and diabetes non-operatively with daily dressing changes, and we believe that this may result in better functional outcomes, ambulatory status, and lower amputation rates. METHODS: A retrospective review of patients with diabetes and foot burns admitted to an ABA verified regional burn center was conducted. The primary outcome was amputation. Secondary outcomes were ambulatory status, wound closure, and infection. Rank sum and fisher exact tests were performed to compare patient demographics, comorbidities, uncontrolled DM (A1c >9%), and burn characteristics between patients who were treated surgically and those who received daily wound care only. These associations were subsequently evaluated with odds ratios (OR) and 95% confidence intervals (CI). A multivariable logistic regression was performed to evaluate for possible differentiating factors that resulted in maintaining ambulatory status at completion of burn care. Statistical significance was defined as p< .05. RESULTS: Of 75 patients identified, median TBSA burned was 2% (IQR 2), and 61% (n=46) had full thickness burns. Mean A1c at admission was 9% (SD 2). In terms of management, 9% (n=7) were treated with debridement and/or skin grafting, and 9% (n=7) later required lower extremity amputations. Infection during first admission developed in 8% (n=6). At completion of burn care, 73% had normal or same ambulatory status, and older patients were less likely to maintain ambulatory status (p=.009, OR=0.92, 95% CI=0.86-0.98). Median time to wound closure was 95 (IQR 130) days, and 12% (n=9) of wounds never fully closed. Burn depth (second vs third degree), burn location (plantar burn vs other areas), uncontrolled DM, and surgical treatment did not result in a statistically significant difference in maintaining ambulatory status at completion of burn care. CONCLUSIONS: Diabetic patients with foot burns are best managed non-operatively with daily dressing changes, and should be allowed to heal secondarily. This may result in a longer time to close the wounds, but the amputation rates were much lower when compared to surgical management. However, 5% of our cohort developed diabetic foot ulcers at completion of burn care, which is a complex disease process that carries a dire prognosis. Oxford University Press 2022-03-23 /pmc/articles/PMC8946110/ http://dx.doi.org/10.1093/jbcr/irac012.230 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the American Burn Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Surgical Care, Acute Non-reconstructive 1
Choi, Katherine J
Gillenwater, Justin
Pham, Christopher H
Sheckter, Clifford C
Collier, Zachary J
Dang, Justin
Huang, Samantha
Yenikomshian, Haig A
Garner, Warren L
602 Foot burns in diabetic patients: A single center experience
title 602 Foot burns in diabetic patients: A single center experience
title_full 602 Foot burns in diabetic patients: A single center experience
title_fullStr 602 Foot burns in diabetic patients: A single center experience
title_full_unstemmed 602 Foot burns in diabetic patients: A single center experience
title_short 602 Foot burns in diabetic patients: A single center experience
title_sort 602 foot burns in diabetic patients: a single center experience
topic Surgical Care, Acute Non-reconstructive 1
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946110/
http://dx.doi.org/10.1093/jbcr/irac012.230
work_keys_str_mv AT choikatherinej 602footburnsindiabeticpatientsasinglecenterexperience
AT gillenwaterjustin 602footburnsindiabeticpatientsasinglecenterexperience
AT phamchristopherh 602footburnsindiabeticpatientsasinglecenterexperience
AT shecktercliffordc 602footburnsindiabeticpatientsasinglecenterexperience
AT collierzacharyj 602footburnsindiabeticpatientsasinglecenterexperience
AT dangjustin 602footburnsindiabeticpatientsasinglecenterexperience
AT huangsamantha 602footburnsindiabeticpatientsasinglecenterexperience
AT yenikomshianhaiga 602footburnsindiabeticpatientsasinglecenterexperience
AT garnerwarrenl 602footburnsindiabeticpatientsasinglecenterexperience