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The Multi-Kinase Inhibitor EC-70124 Is a Promising Candidate for the Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia

SIMPLE SUMMARY: Patients with AML harboring constitutively active mutations in the FLT3 receptor generally have a poor prognosis (FLT3-ITD(MUT)). Despite the fact that several FLT3 inhibitors have been developed, clinical responses are commonly partial or not durable, highlighting the need for new m...

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Detalles Bibliográficos
Autores principales:	Lopez-Millan, Belen, Costales, Paula, Gutiérrez-Agüera, Francisco, Díaz de la Guardia, Rafael, Roca-Ho, Heleia, Vinyoles, Meritxell, Rubio-Gayarre, Alba, Safi, Rémi, Castaño, Julio, Romecín, Paola Alejandra, Ramírez-Orellana, Manuel, Anguita, Eduardo, Jeremias, Irmela, Zamora, Lurdes, Rodríguez-Manzaneque, Juan Carlos, Bueno, Clara, Morís, Francisco, Menendez, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946166/ https://www.ncbi.nlm.nih.gov/pubmed/35326743 http://dx.doi.org/10.3390/cancers14061593

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