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Aptamer Targets Triple-Negative Breast Cancer through Specific Binding to Surface CD49c

SIMPLE SUMMARY: Targeted therapy directed against many biomarkers has not shown significant improvement in outcome in TNBC, and therefore it is urgent to discover more biomarker candidates. Here, we found a DNA aptamer that bound to TNBC cells and identified CD49c as a specific surface marker for TN...

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Detalles Bibliográficos
Autores principales: Wan, Quanyuan, Zeng, Zihua, Qi, Jianjun, Zhao, Yingxin, Liu, Xiaohui, Chen, Zhenghu, Zhou, Haijun, Zu, Youli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946172/
https://www.ncbi.nlm.nih.gov/pubmed/35326720
http://dx.doi.org/10.3390/cancers14061570