Is There a Role for Epigenetic Therapies in Modulating DNA Damage Repair Pathways to Enhance Chemotherapy and Overcome Drug Resistance?

SIMPLE SUMMARY: Epigenetic changes in a cell’s genome can cause the inactivation of genes and affect how tumours respond to chemotherapy. These epigenetic changes do not alter the DNA sequence and small molecule inhibitors of maintenance of the epigenetic state can change the sensitivity of a tumour...

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Detalles Bibliográficos
Autores principales: Garner, Ian Matthew, Brown, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946236/
https://www.ncbi.nlm.nih.gov/pubmed/35326684
http://dx.doi.org/10.3390/cancers14061533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946236/
https://www.ncbi.nlm.nih.gov/pubmed/35326684
http://dx.doi.org/10.3390/cancers14061533

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