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The Fra-1/AP-1 Oncoprotein: From the “Undruggable” Transcription Factor to Therapeutic Targeting
SIMPLE SUMMARY: Cancer-associated mortality largely depends on metastatic dissemination. Metastasizing cancer cells exhibit drastic phenotypic changes, including the ability to migrate, invade surrounding tissues, survive in the bloodstream, adapt to different microenvironments, and resist to therap...
Autores principales: | Casalino, Laura, Talotta, Francesco, Cimmino, Amelia, Verde, Pasquale |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946526/ https://www.ncbi.nlm.nih.gov/pubmed/35326630 http://dx.doi.org/10.3390/cancers14061480 |
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