Real-World Data on Detection of Germline and Somatic Pathogenic/Likely Pathogenic Variants in BRCA1/2 and Other Susceptibility Genes in Ovarian Cancer Patients Using Next Generation Sequencing

SIMPLE SUMMARY: Genotyping of BRCA genes is required for treatment with PARP inhibitors. Purposing to address treatment needs and familial cancer risk, the aim of our study was to introduce the most appropriate testing workflow in epithelial ovarian cancer patients (EOC) using germline and tumor gen...

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Detalles Bibliográficos
Autores principales: Stegel, Vida, Blatnik, Ana, Škof, Erik, Dragoš, Vita Šetrajčič, Krajc, Mateja, Gregorič, Brigita, Škerl, Petra, Strojnik, Ksenija, Klančar, Gašper, Banjac, Marta, Žgajnar, Janez, Ravnik, Maja, Novaković, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946582/
https://www.ncbi.nlm.nih.gov/pubmed/35326583
http://dx.doi.org/10.3390/cancers14061434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946582/
https://www.ncbi.nlm.nih.gov/pubmed/35326583
http://dx.doi.org/10.3390/cancers14061434

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