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Ketamine Improves Desensitization of µ-Opioid Receptors Induced by Repeated Treatment with Fentanyl but Not with Morphine

The issue of tolerance to continuous or repeated administration of opioids should be addressed. The ability of ketamine to improve opioid tolerance has been reported in clinical studies, and its mechanism of tolerance may involve improved desensitization of μ-opioid receptors (MORs). We measured cha...

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Detalles Bibliográficos
Autores principales:	Mizobuchi, Yusuke, Miyano, Kanako, Manabe, Sei, Uezono, Eiko, Komatsu, Akane, Kuroda, Yui, Nonaka, Miki, Matsuoka, Yoshikazu, Sato, Tetsufumi, Uezono, Yasuhito, Morimatsu, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946650/ https://www.ncbi.nlm.nih.gov/pubmed/35327617 http://dx.doi.org/10.3390/biom12030426

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