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Early Endosomal Vps34-Derived Phosphatidylinositol-3-Phosphate Is Indispensable for the Biogenesis of the Endosomal Recycling Compartment

Phosphatidylinositol-3-phosphate (PI3P), a major identity tag of early endosomes (EEs), provides a platform for the recruitment of numerous cellular proteins containing an FYVE or PX domain that is required for PI3P-dependent maturation of EEs. Most of the PI3P in EEs is generated by the activity of...

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Detalles Bibliográficos
Autores principales: Marcelić, Marina, Mahmutefendić Lučin, Hana, Jurak Begonja, Antonija, Blagojević Zagorac, Gordana, Lučin, Pero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946653/
https://www.ncbi.nlm.nih.gov/pubmed/35326413
http://dx.doi.org/10.3390/cells11060962