Batch Effects during Human Bone Marrow Stromal Cell Propagation Prevail Donor Variation and Culture Duration: Impact on Genotype, Phenotype and Function

Donor variation is a prominent critical issue limiting the applicability of cell-based therapies. We hypothesized that batch effects during propagation of bone marrow stromal cells (BMSCs) in human platelet lysate (hPL), replacing fetal bovine serum (FBS), can affect phenotypic and functional variab...

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Detalles Bibliográficos
Autores principales: Brachtl, Gabriele, Poupardin, Rodolphe, Hochmann, Sarah, Raninger, Anna, Jürchott, Karsten, Streitz, Mathias, Schlickeiser, Stephan, Oeller, Michaela, Wolf, Martin, Schallmoser, Katharina, Volk, Hans-Dieter, Geissler, Sven, Strunk, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946746/
https://www.ncbi.nlm.nih.gov/pubmed/35326396
http://dx.doi.org/10.3390/cells11060946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946746/
https://www.ncbi.nlm.nih.gov/pubmed/35326396
http://dx.doi.org/10.3390/cells11060946

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