A Factor H-Fc fusion protein increases complement-mediated opsonophagocytosis and killing of community associated methicillin-resistant Staphylococcus aureus

Staphylococcus aureus employs a multitude of immune-evasive tactics to circumvent host defenses including the complement system, a component of innate immunity central to controlling bacterial infections. With antibiotic resistance becoming increasingly common, there is a dire need for novel therapi...

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Detalles Bibliográficos
Autores principales: Sage, Megan A. G., Cranmer, Katelyn D., Semeraro, Michele L., Ma, Shelby, Galkina, Elena V., Tran, Y., Wycoff, Keith L., Sharp, Julia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946749/
https://www.ncbi.nlm.nih.gov/pubmed/35324969
http://dx.doi.org/10.1371/journal.pone.0265774

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