Functional Role of microRNAs in Regulating Cardiomyocyte Death

microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein, we present an updated and comprehensive overview of the functional involvement of miRs in the regulation of cardiomyoc...

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Detalles Bibliográficos
Autores principales: Kansakar, Urna, Varzideh, Fahimeh, Mone, Pasquale, Jankauskas, Stanislovas S., Santulli, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946783/
https://www.ncbi.nlm.nih.gov/pubmed/35326433
http://dx.doi.org/10.3390/cells11060983
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author Kansakar, Urna
Varzideh, Fahimeh
Mone, Pasquale
Jankauskas, Stanislovas S.
Santulli, Gaetano
author_facet Kansakar, Urna
Varzideh, Fahimeh
Mone, Pasquale
Jankauskas, Stanislovas S.
Santulli, Gaetano
author_sort Kansakar, Urna
collection PubMed
description microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein, we present an updated and comprehensive overview of the functional involvement of miRs in the regulation of cardiomyocyte death, a central event in acute myocardial infarction, ischemia/reperfusion, and heart failure. Specifically, in this systematic review we are focusing on necrosis, apoptosis, and autophagy.
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spelling pubmed-89467832022-03-25 Functional Role of microRNAs in Regulating Cardiomyocyte Death Kansakar, Urna Varzideh, Fahimeh Mone, Pasquale Jankauskas, Stanislovas S. Santulli, Gaetano Cells Review microRNAs (miRNA, miRs) play crucial roles in cardiovascular disease regulating numerous processes, including inflammation, cell proliferation, angiogenesis, and cell death. Herein, we present an updated and comprehensive overview of the functional involvement of miRs in the regulation of cardiomyocyte death, a central event in acute myocardial infarction, ischemia/reperfusion, and heart failure. Specifically, in this systematic review we are focusing on necrosis, apoptosis, and autophagy. MDPI 2022-03-12 /pmc/articles/PMC8946783/ /pubmed/35326433 http://dx.doi.org/10.3390/cells11060983 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kansakar, Urna
Varzideh, Fahimeh
Mone, Pasquale
Jankauskas, Stanislovas S.
Santulli, Gaetano
Functional Role of microRNAs in Regulating Cardiomyocyte Death
title Functional Role of microRNAs in Regulating Cardiomyocyte Death
title_full Functional Role of microRNAs in Regulating Cardiomyocyte Death
title_fullStr Functional Role of microRNAs in Regulating Cardiomyocyte Death
title_full_unstemmed Functional Role of microRNAs in Regulating Cardiomyocyte Death
title_short Functional Role of microRNAs in Regulating Cardiomyocyte Death
title_sort functional role of micrornas in regulating cardiomyocyte death
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946783/
https://www.ncbi.nlm.nih.gov/pubmed/35326433
http://dx.doi.org/10.3390/cells11060983
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