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Divergent Metabolic Effects of Metformin Merge to Enhance Eicosapentaenoic Acid Metabolism and Inhibit Ovarian Cancer In Vivo
SIMPLE SUMMARY: Although the anticancer effects of metformin are well studied, its effect on energy metabolism of cancer cells remains elusive. Metformin can alter the metabolism of cells either by activating AMPK or inhibiting the mitochondrial respiratory chain complex. The aim of the study was to...
Autores principales: | Udumula, Mary P., Poisson, Laila M., Dutta, Indrani, Tiwari, Nivedita, Kim, Seongho, Chinna-Shankar, Jasdeep, Allo, Ghassan, Sakr, Sharif, Hijaz, Miriana, Munkarah, Adnan R., Giri, Shailendra, Rattan, Ramandeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946838/ https://www.ncbi.nlm.nih.gov/pubmed/35326656 http://dx.doi.org/10.3390/cancers14061504 |
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