Cargando…

Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment

Free light chains kappa (FLCκ) in cerebrospinal fluid (CSF) are a part of the intrathecal immune response. This observational study was conducted to investigate the effects of different disease-modifying therapies (DMT) on the humoral intrathecal immune response in the CSF of patients with multiple...

Descripción completa

Detalles Bibliográficos
Autores principales:	Süße, Marie, Konen, Franz Felix, Schwenkenbecher, Philipp, Budde, Kathrin, Nauck, Matthias, Grothe, Matthias, Hannich, Malte Johannes, Skripuletz, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947149/ https://www.ncbi.nlm.nih.gov/pubmed/35328273 http://dx.doi.org/10.3390/diagnostics12030720

Ejemplares similares

Kappa Free Light Chains in Cerebrospinal Fluid in Inflammatory and Non-Inflammatory Neurological Diseases
por: Konen, Franz Felix, et al.
Publicado: (2022)

The Influence of Renal Function Impairment on Kappa Free Light Chains in Cerebrospinal Fluid
por: Konen, Franz F, et al.
Publicado: (2021)

Free light chains kappa can differentiate between myelitis and noninflammatory myelopathy
por: Süße, Marie, et al.
Publicado: (2020)

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern
por: Hannich, Malte Johannes, et al.
Publicado: (2021)

A New Laboratory Workflow Integrating the Free Light Chains Kappa Quotient into Routine CSF Analysis
por: Hannich, Malte Johannes, et al.
Publicado: (2022)

The Increasing Role of Kappa Free Light Chains in the Diagnosis of Multiple Sclerosis
por: Konen, Franz Felix, et al.
Publicado: (2021)

Reiber’s Diagram for Kappa Free Light Chains: The New Standard for Assessing Intrathecal Synthesis?
por: Schwenkenbecher, Philipp, et al.
Publicado: (2019)

Diagnostic Cerebrospinal Fluid Biomarker in Early and Late Onset Multiple Sclerosis
por: Konen, Franz Felix, et al.
Publicado: (2022)

The Persisting Significance of Oligoclonal Bands in the Dawning Era of Kappa Free Light Chains for the Diagnosis of Multiple Sclerosis
por: Schwenkenbecher, Philipp, et al.
Publicado: (2018)

The Impact of Immunomodulatory Treatment on Kappa Free Light Chains as Biomarker in Neuroinflammation
por: Konen, Franz Felix, et al.
Publicado: (2020)

Intrathecal kappa free light chains as markers for multiple sclerosis
por: Vecchio, D., et al.
Publicado: (2020)

Leistungsfähigkeit der McDonald-Kriterien von 2017
por: Konen, Franz Felix, et al.
Publicado: (2022)

Saliva Free Light Chains in Patients with Neuro-Sjögren
por: Konen, Franz Felix, et al.
Publicado: (2022)

Impact of the McDonald Criteria 2017 on Early Diagnosis of Relapsing-Remitting Multiple Sclerosis
por: Schwenkenbecher, Philipp, et al.
Publicado: (2019)

Diagnostic accuracy of intrathecal kappa free light chains compared with OCBs in MS
por: Duell, Frida, et al.
Publicado: (2020)

Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing–remitting multiple sclerosis
por: Rosenstein, Igal, et al.
Publicado: (2023)

Clinically Isolated Syndrome According to McDonald 2010: Intrathecal IgG Synthesis Still Predictive for Conversion to Multiple Sclerosis
por: Schwenkenbecher, Philipp, et al.
Publicado: (2017)

Intrathecal synthesis of anti-Hu antibodies distinguishes patients with paraneoplastic peripheral neuropathy and encephalitis
por: Schwenkenbecher, Philipp, et al.
Publicado: (2016)

Intrathecal Antibody Production Against Epstein-Barr, Herpes Simplex, and Other Neurotropic Viruses in Autoimmune Encephalitis
por: Schwenkenbecher, Philipp, et al.
Publicado: (2021)

Kappa free light chains index in multiple sclerosis very long-term prognosis
por: Arroyo-Pereiro, Pablo, et al.
Publicado: (2023)

The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes
por: Bertram, Dominic, et al.
Publicado: (2023)

The Seasonal Fluctuation of Fatigue in Multiple Sclerosis
por: Grothe, Matthias, et al.
Publicado: (2022)

Severe Anti-N-Methyl-D-Aspartate Receptor Encephalitis Under Immunosuppression After Liver Transplantation
por: Konen, Franz Felix, et al.
Publicado: (2019)

Evidence for an Intrathecal Immunoglobulin Synthesis by Kappa Free Light Chains in Neurological Patients with an Isolated Band in Isoelectric Focusing
por: Weiss, Bastian, et al.
Publicado: (2022)

The Influence of the Ventricular-Lumbar Gradient on Cerebrospinal Fluid Analysis in Serial Samples
por: Konen, Franz Felix, et al.
Publicado: (2022)

High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis
por: Castillo-Villalba, Jéssica, et al.
Publicado: (2022)

Epileptic seizures in multiple sclerosis: prevalence, competing causes and diagnostic accuracy
por: Neuß, Friederike, et al.
Publicado: (2020)

The Influence of Blood Contamination on Cerebrospinal Fluid Diagnostics
por: Schwenkenbecher, Philipp, et al.
Publicado: (2019)

Ocrelizumab Depletes CD20(+) T Cells in Multiple Sclerosis Patients
por: Gingele, Stefan, et al.
Publicado: (2018)

The Use of Kappa Free Light Chains to Diagnose Multiple Sclerosis
por: Arneth, Borros, et al.
Publicado: (2022)

Restricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinations
Publicado: (1993)

Experience in Multiple Sclerosis Patients with COVID-19 and Disease-Modifying Therapies: A Review of 873 Published Cases
por: Möhn, Nora, et al.
Publicado: (2020)

Stem Cell Therapy in Neuroimmunological Diseases and Its Potential Neuroimmunological Complications
por: Konen, Franz Felix, et al.
Publicado: (2022)

Kappa light-chain amyloidosis of gastrointestinal tract
por: Hashimoto, Rintaro, et al.
Publicado: (2019)

Sequence similarities among kappa IIIb chains of monoclonal human IgM kappa autoantibodies
Publicado: (1984)

Cerebrospinal Fluid Immunoglobulin Kappa Light Chain in Clinically Isolated Syndrome and Multiple Sclerosis
por: Senel, Makbule, et al.
Publicado: (2014)

Kappa-Free Light Chains in CSF Predict Early Multiple Sclerosis Disease Activity
por: Berek, Klaus, et al.
Publicado: (2021)

Alzheimer’s disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C
por: Konen, Franz Felix, et al.
Publicado: (2023)

Atypical Nodular Pulmonary Kappa Light-Chain Deposition
por: Nellipudi, Jessy, et al.
Publicado: (2021)

Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A consensus statement
por: Hegen, Harald, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1fn1nsdm287flrkaqc55nrib7c