Cargando…
Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine
We describe a case of Vogt-Koyanagi-Harada (VKH) disease exacerbation after COVID-19 vaccination. A 46-year-old woman presented with a bilateral granulomatous uveitis 2 days after the first dose of COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech), and was diagnosed with a complete Vogt-Koyanagi-Ha...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947156/ https://www.ncbi.nlm.nih.gov/pubmed/35326462 http://dx.doi.org/10.3390/cells11061012 |
_version_ | 1784674371990716416 |
---|---|
author | De Domingo, Begoña López, Miguel Lopez-Valladares, Maria Ortegon-Aguilar, Esperanza Sopeña-Perez-Argüelles, Bernardo Gonzalez, Francisco |
author_facet | De Domingo, Begoña López, Miguel Lopez-Valladares, Maria Ortegon-Aguilar, Esperanza Sopeña-Perez-Argüelles, Bernardo Gonzalez, Francisco |
author_sort | De Domingo, Begoña |
collection | PubMed |
description | We describe a case of Vogt-Koyanagi-Harada (VKH) disease exacerbation after COVID-19 vaccination. A 46-year-old woman presented with a bilateral granulomatous uveitis 2 days after the first dose of COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech), and was diagnosed with a complete Vogt-Koyanagi-Harada (VKH) disease 4 days after receiving the second dose of the vaccine. Three weeks before the first dose, she had been consulted for blurred vision and mild headaches. The case resolved with high dose intravenous corticosteroids, followed by oral prednisone. The close temporal relationship between the COVID-19 vaccine doses and the worsening of VKH symptoms strongly suggests COVID-19 vaccination as the trigger of its exacerbation. |
format | Online Article Text |
id | pubmed-8947156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89471562022-03-25 Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine De Domingo, Begoña López, Miguel Lopez-Valladares, Maria Ortegon-Aguilar, Esperanza Sopeña-Perez-Argüelles, Bernardo Gonzalez, Francisco Cells Case Report We describe a case of Vogt-Koyanagi-Harada (VKH) disease exacerbation after COVID-19 vaccination. A 46-year-old woman presented with a bilateral granulomatous uveitis 2 days after the first dose of COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech), and was diagnosed with a complete Vogt-Koyanagi-Harada (VKH) disease 4 days after receiving the second dose of the vaccine. Three weeks before the first dose, she had been consulted for blurred vision and mild headaches. The case resolved with high dose intravenous corticosteroids, followed by oral prednisone. The close temporal relationship between the COVID-19 vaccine doses and the worsening of VKH symptoms strongly suggests COVID-19 vaccination as the trigger of its exacerbation. MDPI 2022-03-16 /pmc/articles/PMC8947156/ /pubmed/35326462 http://dx.doi.org/10.3390/cells11061012 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report De Domingo, Begoña López, Miguel Lopez-Valladares, Maria Ortegon-Aguilar, Esperanza Sopeña-Perez-Argüelles, Bernardo Gonzalez, Francisco Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title | Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title_full | Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title_fullStr | Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title_full_unstemmed | Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title_short | Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine |
title_sort | vogt-koyanagi-harada disease exacerbation associated with covid-19 vaccine |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947156/ https://www.ncbi.nlm.nih.gov/pubmed/35326462 http://dx.doi.org/10.3390/cells11061012 |
work_keys_str_mv | AT dedomingobegona vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine AT lopezmiguel vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine AT lopezvalladaresmaria vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine AT ortegonaguilaresperanza vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine AT sopenaperezarguellesbernardo vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine AT gonzalezfrancisco vogtkoyanagiharadadiseaseexacerbationassociatedwithcovid19vaccine |