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Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice

Congenital hypothyroidism is a genetic condition in which the thyroid gland fails to produce sufficient thyroid hormone (TH), resulting in metabolic dysfunction and growth retardation. Xb130(−/−) mice exhibit perturbations of thyrocyte cytoskeleton and polarity, and develop postnatal transient growt...

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Detalles Bibliográficos
Autores principales: Sugihara, Junichi, Wong, Aaron, Shimizu, Hiroki, Zhao, Jinbo, Cho, Hae-Ra, Wang, Yingchun, Refetoff, Samuel, Arvan, Peter, Liu, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947158/
https://www.ncbi.nlm.nih.gov/pubmed/35326426
http://dx.doi.org/10.3390/cells11060975

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