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Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice
Congenital hypothyroidism is a genetic condition in which the thyroid gland fails to produce sufficient thyroid hormone (TH), resulting in metabolic dysfunction and growth retardation. Xb130(−/−) mice exhibit perturbations of thyrocyte cytoskeleton and polarity, and develop postnatal transient growt...
Autores principales: | Sugihara, Junichi, Wong, Aaron, Shimizu, Hiroki, Zhao, Jinbo, Cho, Hae-Ra, Wang, Yingchun, Refetoff, Samuel, Arvan, Peter, Liu, Mingyao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947158/ https://www.ncbi.nlm.nih.gov/pubmed/35326426 http://dx.doi.org/10.3390/cells11060975 |
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