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Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study

Anxiety and depression are frequent among patients with breast cancer (BCa). Evidence of the persistence and recovery from these conditions and their determinants is scarce. We describe the occurrence of clinically significant anxiety and depression symptoms and their associated factors among BCa pa...

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Autores principales: Lopes, Catarina, Lopes-Conceição, Luisa, Fontes, Filipa, Ferreira, Augusto, Pereira, Susana, Lunet, Nuno, Araújo, Natália
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947204/
https://www.ncbi.nlm.nih.gov/pubmed/35323373
http://dx.doi.org/10.3390/curroncol29030173
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author Lopes, Catarina
Lopes-Conceição, Luisa
Fontes, Filipa
Ferreira, Augusto
Pereira, Susana
Lunet, Nuno
Araújo, Natália
author_facet Lopes, Catarina
Lopes-Conceição, Luisa
Fontes, Filipa
Ferreira, Augusto
Pereira, Susana
Lunet, Nuno
Araújo, Natália
author_sort Lopes, Catarina
collection PubMed
description Anxiety and depression are frequent among patients with breast cancer (BCa). Evidence of the persistence and recovery from these conditions and their determinants is scarce. We describe the occurrence of clinically significant anxiety and depression symptoms and their associated factors among BCa patients. A total of 506 women admitted in 2012 at the Portuguese Institute of Oncology of Porto were evaluated before treatment and after one, three, and five years (7.9% attrition rate). The five-year prevalence of anxiety and/or depression (Hospital Anxiety and Depression Scale, subscores ≥ 11) was 55.4%. The peak prevalence for anxiety was before treatment (38.0%), and after one year for depression (13.1%). One in five patients with anxiety/depression at baseline had persistent anxiety/depression over time, while only 11% and 22% recovered permanently from anxiety and depression, respectively, during the first year. Higher education, higher income, practicing physical activity, and adequate fruit and vegetable intake were protective factors against anxiety and/or depression. Loss of job and income, anxiolytics and antidepressants, cancer-related neuropathic pain, and mastectomy were associated with higher odds of anxiety and/or depression. These results highlight the importance of monitoring anxiety/depression during the first five years after cancer diagnosis and identify factors associated with these conditions.
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spelling pubmed-89472042022-03-25 Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study Lopes, Catarina Lopes-Conceição, Luisa Fontes, Filipa Ferreira, Augusto Pereira, Susana Lunet, Nuno Araújo, Natália Curr Oncol Article Anxiety and depression are frequent among patients with breast cancer (BCa). Evidence of the persistence and recovery from these conditions and their determinants is scarce. We describe the occurrence of clinically significant anxiety and depression symptoms and their associated factors among BCa patients. A total of 506 women admitted in 2012 at the Portuguese Institute of Oncology of Porto were evaluated before treatment and after one, three, and five years (7.9% attrition rate). The five-year prevalence of anxiety and/or depression (Hospital Anxiety and Depression Scale, subscores ≥ 11) was 55.4%. The peak prevalence for anxiety was before treatment (38.0%), and after one year for depression (13.1%). One in five patients with anxiety/depression at baseline had persistent anxiety/depression over time, while only 11% and 22% recovered permanently from anxiety and depression, respectively, during the first year. Higher education, higher income, practicing physical activity, and adequate fruit and vegetable intake were protective factors against anxiety and/or depression. Loss of job and income, anxiolytics and antidepressants, cancer-related neuropathic pain, and mastectomy were associated with higher odds of anxiety and/or depression. These results highlight the importance of monitoring anxiety/depression during the first five years after cancer diagnosis and identify factors associated with these conditions. MDPI 2022-03-21 /pmc/articles/PMC8947204/ /pubmed/35323373 http://dx.doi.org/10.3390/curroncol29030173 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lopes, Catarina
Lopes-Conceição, Luisa
Fontes, Filipa
Ferreira, Augusto
Pereira, Susana
Lunet, Nuno
Araújo, Natália
Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title_full Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title_fullStr Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title_full_unstemmed Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title_short Prevalence and Persistence of Anxiety and Depression over Five Years since Breast Cancer Diagnosis—The NEON-BC Prospective Study
title_sort prevalence and persistence of anxiety and depression over five years since breast cancer diagnosis—the neon-bc prospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947204/
https://www.ncbi.nlm.nih.gov/pubmed/35323373
http://dx.doi.org/10.3390/curroncol29030173
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