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Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513

MicroRNAs (miRNAs) are small post-transcriptional regulators that offer promising targets for treating complex diseases. To this end, hsa-miR-4513 is an excellent candidate as this gene harbors within its conserved heptametrical seed sequence a frequent polymorphism (rs2168518), which has previously...

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Detalles Bibliográficos
Autores principales: Kiel, Christina, Strunz, Tobias, Hasler, Daniele, Meister, Gunter, Grassmann, Felix, Weber, Bernhard H F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947236/
https://www.ncbi.nlm.nih.gov/pubmed/34605899
http://dx.doi.org/10.1093/hmg/ddab292